Owner The Trustees of the University of Pennsylvania

Inventors Gao, Guangping; Wilson, James M.; Alvira, Mauricio

Agent Davies Collison Cave

Pub. Number AU-A-2012238302

Parent 2011250837

Filing date 10 October 2012

Wipo publication date 1 November 2012

C12N 15/09 Mutation or genetic engineering - Recombinant DNA-technology

A61K 35/76 Medicinal preparations containing material or reaction products thereof with undetermined constitution

A61K 38/00 Medicinal preparations containing peptides

A61K 38/43 Medicinal preparations containing peptides - Enzymes

A61K 48/00 Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

A61P 1/04 Drugs for disorders of the alimentary tract or the digestive system

A61P 3/10 Drugs for disorders of the metabolism

A61P 5/14 Drugs for disorders of the endocrine system

A61P 7/04 Drugs for disorders of the blood or the extracellular fluid

A61P 9/00 Drugs for disorders of the cardiovascular system

A61P 17/06 Drugs for dermatological disorders

A61P 19/02 Drugs for skeletal disorders

A61P 21/00 Drugs for disorders of the muscular or neuromuscular system

A61P 25/00 Drugs for disorders of the nervous system

A61P 29/00 Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

A61P 37/02 Drugs for immunological or allergic disorders

A61P 37/06 Drugs for immunological or allergic disorders

C07K 14/015 Peptides having more than 20 amino acids

C07K 14/075 Peptides having more than 20 amino acids

C12N 1/15 Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/19 Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/21 Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material