Owner Vertex Pharmaceuticals (Canada) Incorporated

Inventors Chan, Chun Kong Laval; Bedard, Jean; Das, Sanjoy Kumar; Nguyen Ba, Nghe; Pereira, Oswy Z.; Reddy, Thumkunta Jagadeeswar; Siddiqui, M. Arshad; Wang, Wuyi; Yannopoulos, Constantin

Agent Griffith Hack

Pub. Number AU-A-2012202716

Parent 2009200430

Filing date 9 May 2012

Wipo publication date 31 May 2012

C07D 333/40 (2006.01) Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

A61K 31/20 (2006.01)

A61K 31/341 (2006.01) - not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine

A61K 31/343 (2006.01) - condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone

A61K 31/381 (2006.01) - having five-membered rings

A61K 31/382 (2006.01) - having six-membered rings, e.g. thioxanthenes

A61K 31/4025 (2006.01) - not condensed and containing further heterocyclic rings, e.g. cromakalim

A61K 31/4035 (2006.01)

A61K 31/404 (2006.01)

A61K 31/41 (2006.01) - having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole

A61K 31/4155 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/42 (2006.01) - Oxazoles

A61K 31/426 (2006.01) - 1,3-Thiazoles

A61K 31/427 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/433 (2006.01) - Thiadiazoles

A61K 31/437 (2006.01)

A61K 31/4436 (2006.01)

A61K 31/4535 (2006.01)

A61K 31/454 (2006.01)

A61K 31/4709 (2006.01) - Non-condensed quinolines containing further heterocyclic rings

A61K 31/4725 (2006.01)

A61K 31/496 (2006.01) - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene

A61K 31/55 - having seven-membered rings, e.g. azelastine, pentylenetetrazole