Owner Vertex Pharmaceuticals Incorporated

Inventors Farmer, Luc; Martinez-Botella, Gabriel; Pierce, Albert; Salituro, Francesco; Wang, Jian; Wannamker, Marion; Wang, Tiansheng

Agent Cullens

Pub. Number AU-A-2012202473

Parent 2007207533

Filing date 30 April 2012

Wipo publication date 17 May 2012

C07D 471/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/517 (2006.01) - ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine

A61K 31/53 (2006.01) - having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine

A61P 25/00 (2006.01) Drugs for disorders of the nervous system

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

A61P 37/00 (2006.01) Drugs for immunological or allergic disorders

C07D 495/10 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms

C07D 519/00 (2006.01) Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups or