Genetic engineering of non-human animals for the production of chimeric antibodies

Details for Australian Patent Application No. 2011234988 (hide)

Owner Ablexis LLC

Inventors Green, Larry; Shizuya, Hiroaki

Agent Davies Collison Cave

Pub. Number AU-A-2011234988

PCT Pub. Number WO2011/123708

Priority 61/319,690 31.03.10 US; 61/361,302 02.07.10 US

Filing date 31 March 2011

Wipo publication date 6 October 2011

International Classifications

C12N 15/13 Mutation or genetic engineering - Immunoglobulins

A01K 67/027 Rearing or breeding animals, not otherwise provided for - New breeds of vertebrates

C07K 16/46 Immunoglobulins, e.g. monoclonal or polyclonal antibodies - Hybrid immunoglobulins

C12N 5/10 Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

C12N 15/62 Mutation or genetic engineering - DNA sequences coding for fusion proteins

Event Publications

18 October 2012 PCT application entered the National Phase

  PCT publication WO2011/123708 Priority application(s): WO2011/123708

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