Compounds (cystein based lipopeptides) and compositions as TLR2 agonists used for treating infections, inflammations, respiratory diseases etc.

Details for Australian Patent Application No. 2011232421 (hide)

Owner IRM LLC

Inventors Wu, Tom Yao-Hsiang; Zou, Yefen; Hoffman, Timothy Z.; Pan, Jianfeng

Agent Davies Collison Cave

Pub. Number AU-A-2011232421

PCT Pub. Number WO2011/119759

Priority 61/316,551 23.03.10 US

Filing date 23 March 2011

Wipo publication date 29 September 2011

International Classifications

C07C 323/60 Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups

A61K 31/17 - having the group NC(O)N or NC(S)N, e.g. urea, thiourea, carmustine

A61K 31/198

A61K 31/661 - Phosphorus acids or esters thereof not having PC bonds, e.g. fosfosal, dichlorvos, malathion

A61K 38/10 Medicinal preparations containing peptides - Peptides having 12 to 20 amino acids

A61P 11/00 Drugs for disorders of the respiratory system

A61P 17/00 Drugs for dermatological disorders

A61P 29/00 Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

A61P 31/00 Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P 35/00 Antineoplastic agents

C07K 5/04 Peptides having up to four amino acids in a fully defined sequence

Event Publications

25 October 2012 PCT application entered the National Phase

  PCT publication WO2011/119759 Priority application(s): WO2011/119759

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