Owner Amgen Inc.

Inventors Chen, Jian J.; Zhong, Wenge; Yang, Bryant; Qian, Wenyuan; Lopez, Patricia; White, Ryan; Weiss, Matthew; Judd, Ted; Powers, Timothy; Cheng, Yuan; Dineen, Thomas; Epstein, Oleg; Low, Jonathan; Marx, Isaac; Minatti, Ana Elena; Paras, Nick A.; Potashman, Michele

Agent Shelston IP

Pub. Number AU-A-2011227501

PCT Pub. Number WO2011/115928

Priority 61/314,024 15.03.10 US

Filing date 14 March 2011

Wipo publication date 22 September 2011

C07D 498/10 Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms

A61K 31/537 - spiro-condensed or forming part of bridged ring systems

A61K 31/5386

A61K 31/547 - spiro-condensed or forming part of bridged ring systems

A61P 25/28 Drugs for disorders of the nervous system

C07D 498/20 Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 513/10 Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups , or

C07D 513/20 Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups , or