Owner AbbVie Inc.

Inventors Li, Yingchun; Gu, Jijie James; Morgan-Lappe, Susan; Chen, Mingjiu; Hsieh, Chung-Ming

Agent Spruson & Ferguson

Pub. Number AU-A-2011223919

PCT Pub. Number WO2011/109298

Priority 61/309,494 02.03.10 US

Filing date 28 February 2011

Wipo publication date 9 September 2011

C07K 16/00 Immunoglobulins, e.g. monoclonal or polyclonal antibodies

A61K 39/395 Medicinal preparations containing antigens or antibodies - Antibodies

A61K 49/00 Preparations for testing

A61P 9/00 Drugs for disorders of the cardiovascular system

A61P 17/06 Drugs for dermatological disorders

A61P 25/28 Drugs for disorders of the nervous system

A61P 35/00 Antineoplastic agents

A61P 43/00 Drugs for specific purposes, not provided for in groups

C07H 21/00 Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

C07K 16/18 Immunoglobulins, e.g. monoclonal or polyclonal antibodies - against material from animals or humans

C07K 17/00 Carrier-bound or immobilised peptides

C12N 1/00 Micro-organisms, e.g. protozoa

C12N 1/15 Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/19 Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/21 Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 5/10 Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

C12N 9/96 Enzymes, e.g. ligases (6.) - Stabilising an enzyme by forming an adduct or a composition

C12N 15/63 Mutation or genetic engineering - Introduction of foreign genetic material using vectors

C12P 21/00 Preparation of peptides or proteins