Owner Amakem NV

Inventors Leysen, Dirk; Defert, Olivier; Kaval, Nadzeya; Blom, Petra; Boland, Sandro

Agent Shelston IP

Pub. Number AU-A-2011222900

PCT Pub. Number WO2011/107608

Priority 1018996.7 10.11.10 GB; 1003395.9 02.03.10 GB

Filing date 4 March 2011

Wipo publication date 9 September 2011

C07D 213/75 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

A61K 31/437

A61K 31/4409 - only substituted in position 4, e.g. isoniazid, iproniazid

A61K 31/443

A61K 31/4433

A61K 31/4436

A61K 31/505 - Pyrimidines

A61P 1/00 Drugs for disorders of the alimentary tract or the digestive system

A61P 9/00 Drugs for disorders of the cardiovascular system

C07D 239/42 Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 401/12 Heterocyclic compounds containing two or more hetero rings

C07D 405/12 Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 409/12 Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 471/04 Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 493/04 Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system