Owner Amgen Inc.

Inventors Paras, Nick A.; Brown, James; Cheng, Yuan; Hitchcock, Stephen; Judd, Ted; Lopez, Patricia; Minatti, Ana Elena; Nixey, Thomas; Powers, Timothy; Tegley, Christopher M.; Xue, Qiufen; Yang, Bryant; Zhong, Wenge

Agent Shelston IP

Pub. Number AU-A-2011207679

PCT Pub. Number WO2011/090911

Priority 61/296,416 19.01.10 US

Filing date 14 January 2011

Wipo publication date 28 July 2011

C07D 215/38 Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems

A61K 31/47 - Quinolines

A61K 31/4709 - Non-condensed quinolines containing further heterocyclic rings

A61P 25/28 Drugs for disorders of the nervous system

C07D 401/10 Heterocyclic compounds containing two or more hetero rings

C07D 403/10 Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 405/04 Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 405/10 Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 405/12 Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 413/10 Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 471/04 Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 471/08 Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 498/08 Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms