Owner Nitto Denko Corporation Quark Pharmaceuticals, Inc.

Inventors Jin, Xiaomei; Yu, Lei; Takahashi, Hirokazu; Tanaka, Yasunobu; Niitsu, Yoshiro; Feinstein, Elena; AvkinNachum, Sharon; Kalinski, Hagar; Mett, Igor; Erlich, Shai; Squiers, Elizabeth C.; Chen, Ning

Agent FB Rice

Pub. Number AU-A-2010328104

PCT Pub. Number WO2011/072082

Priority 61/307,412 23.02.10 US; 61/372,072 09.08.10 US; 61/285,149 09.12.09 US

Filing date 8 December 2010

Wipo publication date 16 June 2011

A61K 31/713 - Double-stranded nucleic acids or oligonucleotides

A61K 31/7088 - Compounds having three or more nucleosides or nucleotides

A61K 48/00 Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

A61P 43/00 Drugs for specific purposes, not provided for in groups

C07H 21/00 Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

C07H 21/02 Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids