Owner F. Hoffmann-La Roche AG

Inventors Blaquiere, Nicole; Do, Steven; Dudley, Danette; Folkes, Adrian J.; Heald, Robert; Heffron, Timothy; Jones, Mark; Kolesnikov, Aleksandr; Ndubaku, Chudi; Olivero, Alan G.; Price, Stephen; Staben, Steven; Wang, Lan

Agent Griffith Hack

Pub. Number AU-A-2010299816

PCT Pub. Number WO2011/036280

Priority 61/330,685 03.05.10 US; 61/246,381 28.09.09 US

Filing date 27 September 2010

Wipo publication date 31 March 2011

C07D 498/04 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms

A61K 31/4162 (2006.01) - condensed with heterocyclic ring systems

A61K 31/4188 (2006.01)

A61K 31/4196 (2006.01) - 1,2,4-Triazoles

A61P 35/00 (2006.01) Antineoplastic agents

C07D 498/14 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 519/00 (2006.01) Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups or