Owner The Cleveland Clinic Foundation

Inventors Penn, Marc S.; Aras, Rahul; Pastore, Joseph; Miller, Timothy R.

Agent Fisher Adams Kelly

Pub. Number AU-A-2010286511

PCT Pub. Number WO2011/026041

Priority 61/237,775 28.08.09 US; 61/334,216 13.05.10 US

Filing date 30 August 2010

Wipo publication date 3 March 2011

A61K 47/42 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Proteins

A61K 31/7105 (2006.01) - Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links

A61K 31/711 (2006.01) - Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links

A61K 38/16 (2006.01) Medicinal preparations containing peptides - Peptides having more than 20 amino acids

A61K 47/48 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates

A61P 9/10 (2006.01) Drugs for disorders of the cardiovascular system