Owner Otsuka Pharmaceutical Co., Ltd.

Inventors Oshima, Kunio; Matsumura, Shuuji; Yamabe, Hokuto; Isono, Naohiro; Takemura, Noriaki; Taira, Shinichi; Oshiyama, Takashi; Menjo, Yasuhiro; Nagase, Tsuyoshi; Ueda, Masataka; Koga, Yasuo; Nakayama, Sunao; Tsujimae, Kenji; Onogawa, Toshiyuki; Tai, Kuninori; Itotani, Motohiro

Agent Freehills

Pub. Number AU-A-2010285621

PCT Pub. Number WO2011/021726

Priority 61/235,983 21.08.09 US; 61/359,686 29.06.10 US; 61/235,973 21.08.09 US; 61/235,981 21.08.09 US

Filing date 20 August 2010

Wipo publication date 24 February 2011

C07D 243/12 (2006.01) Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms

A61K 31/4704 (2006.01) - 2-Quinolinones, e.g. carbostyril

A61K 31/496 (2006.01) - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene

A61K 31/498 (2006.01) - Pyrazines or piperazines ortho- or peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine

A61K 31/4985 (2006.01) - Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/517 (2006.01) - ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine

A61K 31/551 (2006.01) - having two nitrogens as ring hetero atoms, e.g. clozapine, dilazep

A61K 31/553 (2006.01) - having at least one nitrogen and at least one oxygen as ring hetero atoms, e.g. loxapine, staurosporine

A61K 31/554 (2006.01) - having at least one nitrogen and at least one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem

C07D 215/227 (2006.01) Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems

C07D 401/06 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 401/14 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/06 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 403/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 403/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 405/14 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 407/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group

C07D 409/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 409/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 413/06 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 413/12 Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms