Owner Crucell Holland B.V.

Inventors Williamson, Robert Anthony; Wadia, Jehangir; Pascual, Gabriel; Keogh, Elissa

Agent Pizzeys

Pub. Number AU-A-2010282312

PCT Pub. Number WO2011/020079

Priority 61/274,395 13.08.09 US

Filing date 13 August 2010

Wipo publication date 17 February 2011

C07K 16/10 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies

A61K 31/00 (2006.01)

A61K 38/00 (2006.01) Medicinal preparations containing peptides

A61K 39/42 (2006.01) Medicinal preparations containing antigens or antibodies - viral

A61K 47/48 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates

A61P 31/14 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

C12N 5/10 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

C12N 15/13 (2006.01) Mutation or genetic engineering - Immunoglobulins

C12N 15/63 (2006.01) Mutation or genetic engineering - Introduction of foreign genetic material using vectors

G01N 33/53 (2006.01) Investigating or analysing materials by specific methods not covered by groups - Immunoassay