(+) - morphinans as antagonists of Tolllike receptor 9 and therapeutic uses thereof

Details for Australian Patent Application No. 2010273253 (hide)

Owner Mallinckrodt LLC

Inventors Trawick, Bobby N.; Berberich, David W.

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-A-2010273253

PCT Pub. Number WO2011/009015

Priority 61/226,015 16.07.09 US; 61/286,877 16.12.09 US

Filing date 16 July 2010

Wipo publication date 20 January 2011

International Classifications

C07D 217/20 (2006.01) Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems

A61K 31/472 (2006.01) - Non-condensed isoquinolines, e.g. papaverine

A61K 31/485 (2006.01) - Morphinan derivatives, e.g. morphine, codeine

A61K 45/06 (2006.01) Medicinal preparations containing active ingredients not provided for in groups

A61P 25/00 (2006.01) Drugs for disorders of the nervous system

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

C07D 221/28 (2006.01) Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups

C07D 489/00 (2006.01) Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:

Event Publications

9 February 2012 PCT application entered the National Phase

  PCT publication WO2011/009015 Priority application(s): WO2011/009015

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