2,3-fluorinated glycosides as neuraminidase inhibitors and their use as antivirals

Details for Australian Patent Application No. 2010273118 (hide)

Owner The University of British Columbia

Inventors Withers, Stephen; Watts, Andrew Graham; Kim, Jin Hyo; Wennekes, Tom

Agent FB Rice

Pub. Number AU-A-2010273118

PCT Pub. Number WO2011/006237

Priority 61/213,786 15.07.09 US

Filing date 15 July 2010

Wipo publication date 20 January 2011

International Classifications

C07H 5/02 (2006.01) Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium

A61K 31/7012 (2006.01) - Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid

A61P 31/16 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

C07H 13/04 (2006.01) Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids

C07H 13/12 (2006.01) Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids

C07H 15/12 (2006.01) Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals

C07H 15/18 (2006.01) Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals

C12N 9/24 (2006.01) Enzymes, e.g. ligases (6.) - acting on glycosyl compounds (3.2)

Event Publications

2 February 2012 PCT application entered the National Phase

  PCT publication WO2011/006237 Priority application(s): WO2011/006237

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