Design of stable and aggregation free antibody Fc molecules through CH3 domain interface engineering

Details for Australian Patent Application No. 2010270844 (hide)

Owner Amgen Inc.

Inventors Kannan, Gunasekaran; Zhou, Hongxing

Agent Wrays

Pub. Number AU-A-2010270844

PCT Pub. Number WO2011/005621

Priority 61/223,831 08.07.09 US

Filing date 29 June 2010

Wipo publication date 13 January 2011

International Classifications

C07K 16/00 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies

C12P 21/06 (2006.01) Preparation of peptides or proteins - produced by the hydrolysis of a peptide bond, e.g. hydrolysate products

Event Publications

22 December 2011 PCT application entered the National Phase

  PCT publication WO2011/005621 Priority application(s): WO2011/005621

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