Novel (6-oxo-1, 6-dihydro-pyrimidin-2-yl)-amide derivatives, preparation thereof, and pharmaceutical use thereof as AKT(PKB) phosphorylation inhibitors

Details for Australian Patent Application No. 2010267816 (hide)

Owner Sanofi

Inventors Carry, Jean-Christophe; Certal, Victor; Halley, Frank; Karlsson, Karl Andreas; Schio, Laurent; Thompson, Fabienne

Agent Watermark

Pub. Number AU-A-2010267816

PCT Pub. Number WO2011/001114

Priority 0903239 02.07.09 FR; 0957070 09.10.09 FR; 61/241,100 10.09.09 US

Filing date 1 July 2010

Wipo publication date 6 January 2011

International Classifications

C07D 239/36 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

A61K 31/513 (2006.01) - having oxo groups directly attached to the heterocyclic ring, e.g. cytosine

A61K 31/5377 (2006.01)

A61P 35/00 (2006.01) Antineoplastic agents

C07D 239/47 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 403/06 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 403/10 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 403/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 409/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 413/06 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 413/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

Event Publications

16 February 2012 PCT application entered the National Phase

  PCT publication WO2011/001114 Priority application(s): WO2011/001114

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