Benzoxazepines as inhibitors of PI3K/m TOR and methods of their use and manufacture

Details for Australian Patent Application No. 2010254200 (hide)

Owner Exelixis, Inc.

Inventors Aay, Naing; Arcalas, Arlyn; Bowles, Owen Joseph; Bussenius, Joerg; Curtis, Jeffry Kimo; Defina, Steven Charles; Dubenko, Larisa; Harris, Jason R.; Jackson-Ugueto, Eileen E.; Manalo, Jean-Claire Limun; Kim, Angie Inyoung; Pack, Michael; Peto, Csaba J.; Rice, Kenneth D.; Tsang, Tsze H.

Agent A J Park

Pub. Number AU-A-2010254200

PCT Pub. Number WO2010/138487

Priority 61/217,146 26.05.09 US

Filing date 25 May 2010

Wipo publication date 2 December 2010

International Classifications

C07D 413/04 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

A61K 31/553 (2006.01) - having at least one nitrogen and at least one oxygen as ring hetero atoms, e.g. loxapine, staurosporine

A61P 35/00 (2006.01) Antineoplastic agents

C07D 413/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 417/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

C07D 451/02 (2006.01) Heterocyclic compounds containing condensed hetero ring systems

C07D 471/10 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 487/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

C07D 487/08 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

Event Publications

8 December 2011 PCT application entered the National Phase

  PCT publication WO2010/138487 Priority application(s): WO2010/138487

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