Owner F. Hoffmann-La Roche AG

Inventors Banner, David; Hilpert, Hans; Humm, Roland; Mauser, Harald; Mayweg, Alexander V.; Ricklin, Fabienne; RogersEvans, Mark

Agent Spruson & Ferguson

Pub. Number AU-A-2010244470

PCT Pub. Number WO2010/128058

Priority 09159740.1 08.05.09 EP

Filing date 5 May 2010

Wipo publication date 11 November 2010

C07D 239/22 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

A61K 31/513 (2006.01) - having oxo groups directly attached to the heterocyclic ring, e.g. cytosine

A61K 31/527 (2006.01) - spiro-condensed

A61P 3/10 (2006.01) Drugs for disorders of the metabolism

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 409/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 413/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 417/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

C07D 471/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 495/04 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms