Owner Novartis AG Astex Therapeutics Limited

Inventors Howard, Steven; Mortenson, Paul Neil; Hiscock, Steven Douglas; Woolford, Alison Jo-Anne; Woodhead, Andrew James; Chessari, Gianni; O'Reilly, Marc; Congreve, Miles Stuart; Dagostin, Claudio; Cho, Young Shin; Yang, Fan; Chen, Christine Hiu-Tung; Brain, Christopher Thomas; Lagu, Bharat; Wang, Yaping; Kim, Sunkyu; Grialdes, John; Luzzio, Michael Joseph; Perez, Lawrence Blas; Yipin, Lu

Agent Davies Collison Cave

Pub. Number AU-A-2010243353

PCT Pub. Number WO2010/125402

Priority 61/174,293 30.04.09 US

Filing date 30 April 2010

Wipo publication date 4 November 2010

C07D 233/22 (2006.01) Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings

A61K 31/4164 (2006.01) - 1,3-Diazoles

A61K 31/4178 (2006.01)

A61P 35/00 (2006.01) Antineoplastic agents

C07D 235/12 (2006.01) Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings

C07D 401/06 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 401/10 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 401/14 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 409/10 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 409/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 413/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 417/10 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group