Methods and compositions for the specific inhibition of KRAS by asymmetric double-stranded RNA

Details for Australian Patent Application No. 2010232410 (hide)

Owner Dicerna Pharmaceuticals, Inc.

Inventors Brown, Bob D.

Agent Wrays

Pub. Number AU-A-2010232410

PCT Pub. Number WO2010/115206

Priority 12/704,256 11.02.10 US; 61/257,810 03.11.09 US; 61/257,820 03.11.09 US; 61/309,266 01.03.10 US; 12/642,371 18.12.09 US; 61/166,578 03.04.09 US; 61/184,735 05.06.09 US; 61/166,559 03.04.09 US; 61/183,818 03.06.09 US; PCT/ US2009/005214 17.09.09 US; 61/174,279 30.04.09 US; 61/285,925 11.12.09 US; 12/642,404 18.12.09 US; 61/183,815 03.06.09 US; 61/174,306 30.04.09 US; 12/642,264 18.12.09 US

Filing date 5 April 2010

Wipo publication date 7 October 2010

International Classifications

A61K 31/713 (2006.01) - Double-stranded nucleic acids or oligonucleotides

C07H 21/02 (2006.01) Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

C12N 5/00 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines

C12P 19/34 (2006.01) Preparation of compounds containing saccharide radicals

Event Publications

27 October 2011 PCT application entered the National Phase

  PCT publication WO2010/115206 Priority application(s): WO2010/115206

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