8-substituted quinolines and related analogs as sirtuin modulators

Details for Australian Patent Application No. 2010221417 (hide)

Owner Sirtris Pharmaceuticals, Inc.

Inventors Vu, Chi B.; Casaubon, Rebecca L.

Agent Davies Collison Cave

Pub. Number AU-A-2010221417

PCT Pub. Number WO2010/101949

Priority 61/156,749 02.03.09 US

Filing date 2 March 2010

Wipo publication date 10 September 2010

International Classifications

C07D 215/48 (2006.01) Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems

A61K 31/4375 (2006.01)

A61K 31/47 (2006.01) - Quinolines

A61K 31/4709 (2006.01) - Non-condensed quinolines containing further heterocyclic rings

A61K 31/497 (2006.01)

A61K 31/501 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/519 (2006.01) - ortho- or peri-condensed with heterocyclic rings

A61K 31/5377 (2006.01)

A61K 31/538 (2006.01)

A61P 3/00 (2006.01) Drugs for disorders of the metabolism

A61P 5/50 (2006.01) Drugs for disorders of the endocrine system

A61P 9/00 (2006.01) Drugs for disorders of the cardiovascular system

A61P 35/02 (2006.01) Antineoplastic agents

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 401/14 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 413/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 417/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

C07D 417/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

C07D 487/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

Event Publications

22 September 2011 PCT application entered the National Phase

  PCT publication WO2010/101949 Priority application(s): WO2010/101949

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