Combination of a nucleoside polymerase inhibitor with a macrocyclic protease inhibitor and use thereof in the treatment of hepatitis C, liver fibrosis and impaired liver function

Details for Australian Patent Application No. 2010217818 (hide)

Owner Pharmasset, Inc. F. Hoffmann-La Roche Ltd Roche Palo Alto LLC Hoffmann-La Roche Inc.

Inventors Porter, Steven B.; Bradford, Williamson Ziegler; Smith, Patrick F.; Yetzer, Ellen S.; De La Rosa, Abel; Rogers, Michael D.; Symonds, William T.

Agent Griffith Hack

Pub. Number AU-A-2010217818

PCT Pub. Number WO2010/099458

Priority 61/257,367 02.11.09 US; 61/156,414 27.02.09 US

Filing date 26 February 2010

Wipo publication date 2 September 2010

International Classifications

A61K 31/4709 (2006.01) - Non-condensed quinolines containing further heterocyclic rings

A61K 31/7068 (2006.01)

A61P 1/16 (2006.01) Drugs for disorders of the alimentary tract or the digestive system

A61P 31/14 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Event Publications

18 August 2011 PCT application entered the National Phase

  PCT publication WO2010/099458 Priority application(s): WO2010/099458

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