Owner Amgen Inc.

Inventors Boezio, Alessandro; Cheng, Alan C.; Coats, James R.; Copeland, Katrina W.; Graceffa, Russell; Harmange, Jean-Christophe; Huang, Hongbing; La, Daniel; Olivieri, Philip R.; Peterson, Emily A.; Schenkel, Laurie

Agent Shelston IP

Pub. Number AU-B-2010216239

PCT Pub. Number WO2010/096314

Priority 61/153,580 18.02.09 US

Filing date 10 February 2010

Wipo publication date 26 August 2010

Acceptance publication date 14 June 2012

C07D 401/14 (2006.01) Heterocyclic compounds containing two or more hetero rings

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/53 (2006.01) - having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine

A61K 31/5355 (2006.01) - Non-condensed oxazines containing further heterocyclic rings

A61P 35/00 (2006.01) Antineoplastic agents

C07D 403/04 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 403/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 405/14 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 409/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 413/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 417/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group