Synthetic RNA-based agonists of TLR7

Details for Australian Patent Application No. 2010213795 (hide)

Owner Idera Pharmaceuticals, Inc.

Inventors Lan, Tao; Kandimalla, Ekambar R.; Wang, Daqing; Agrawal, Sudhir

Agent Freehills

Pub. Number AU-A-2010213795

PCT Pub. Number WO2010/093705

Priority 61/151,211 10.02.09 US

Filing date 10 February 2010

Wipo publication date 19 August 2010

International Classifications

C12N 15/117 (2010.01) Mutation or genetic engineering - Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs

A61K 39/39 (2006.01) Medicinal preparations containing antigens or antibodies - characterised by the immunostimulating additives, e.g. chemical adjuvants

A61K 31/7115 (2006.01) - Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine

A61K 31/7125 (2006.01) - Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiesters

C07H 21/02 (2006.01) Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Event Publications

4 August 2011 PCT application entered the National Phase

  PCT publication WO2010/093705 Priority application(s): WO2010/093705

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