Owner MERCK SERONO S.A.

Inventors Crosignani, Stefano; Jorand-Lebrun, Catherine; Cleva, Christophe; Pretre, Adeline

Agent Griffith Hack

Pub. Number AU-A-2010212970

PCT Pub. Number WO2010/092043

Priority 09152711.9 12.02.09 EP; 61/207,778 17.02.09 US

Filing date 9 February 2010

Wipo publication date 19 August 2010

C07C 59/70 (2006.01) Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O-metal, CHO, keto, ether, groups, groups, or groups

A61K 31/192 (2006.01)

A61P 7/06 (2006.01) Drugs for disorders of the blood or the extracellular fluid

A61P 17/00 (2006.01) Drugs for dermatological disorders

A61P 25/28 (2006.01) Drugs for disorders of the nervous system

A61P 37/00 (2006.01) Drugs for immunological or allergic disorders

C07D 213/30 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/65 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/71 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/76 (1970.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 233/64 (2006.01) Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings

C07D 277/24 (2006.01) Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D 295/096 (1970.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 333/28 (2006.01) Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings