Owner Pharmacopeia, LLC N.V. Organon

Inventors Palin, Ronald; Ratcliffe, Paul David; Kultgen, Steven G.; Ho, Koc-Kan; Roughton, Andrew Laird; Ohlmeyer, Michael

Agent Spruson & Ferguson

Pub. Number AU-A-2010210776

PCT Pub. Number WO2010/091009

Priority 09152068.4 04.02.09 EP; 61/149,722 04.02.09 US

Filing date 2 February 2010

Wipo publication date 12 August 2010

C07D 261/18 (2006.01) Heterocyclic compounds having nitrogen and oxygen as the only ring hetero atoms

A61K 31/42 (2006.01) - Oxazoles

A61K 31/422 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/4439 (2006.01)

A61K 31/4453 (2006.01) - only substituted in position 1, e.g. propipocaine, diperodon

A61K 31/4468 (2006.01) - having a nitrogen atom directly attached in position 4, e.g. clebopride, fentanyl

A61K 31/45 (2006.01) - having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide

A61K 31/5377 (2006.01)

A61P 25/00 (2006.01) Drugs for disorders of the nervous system

C07D 413/06 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 413/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms