Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides

Details for Australian Patent Application No. 2010210016 (hide)

Owner Idera Pharmaceuticals, Inc.

Inventors Kandimalla, Ekambar; Bhagat, Lakshmi; Yu, Dong; Agrawal, Sudhir

Agent Freehills

Pub. Number AU-B-2010210016

Parent 2004206820

Filing date 9 August 2010

Wipo publication date 2 September 2010

Acceptance publication date 23 February 2012

International Classifications

C07H 21/00 (2006.01) Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

A61K 31/7088 (2006.01) - Compounds having three or more nucleosides or nucleotides

A61K 48/00 (2006.01) Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

C07H 21/02 (2006.01) Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

C07H 21/04 (2006.01) Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

C12N 15/11 (2006.01) Mutation or genetic engineering - DNA or RNA fragments

C12N 15/117 (2010.01) Mutation or genetic engineering - Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs

C12Q 1/68 (2006.01) Measuring or testing processes involving enzymes or micro-organisms - involving nucleic acids

Event Publications

26 August 2010 Complete Application Filed

2 September 2010 Application Open to Public Inspection

  Published as AU-B-2010210016

23 February 2012 Application Accepted

  Published as AU-B-2010210016

21 June 2012 Standard Patent Sealed

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