Malate salt of N-(4-{ [ 6, 7-bis (methyloxy)-quinolin-4-yl] oxy}phenyl)-N'-(4-fluorophenyl) cyclopropane-1,1-dicarboxamide, and crystalline forms therof for the treatment of cancer

Details for Australian Patent Application No. 2010204619 (hide)

Owner Bristol-Meyers Squibb Company Exelixis, Inc.

Inventors Brown, Adrian, St. Clair; Lamb, Peter; Gallagher, William P.

Agent A J Park

Pub. Number AU-A-2010204619

PCT Pub. Number WO2010/083414

Priority 61/145,421 16.01.09 US

Filing date 15 January 2010

Wipo publication date 22 July 2010

International Classifications

C07D 215/227 (2006.01) Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems

A61K 31/47 (2006.01) - Quinolines

A61P 35/00 (2006.01) Antineoplastic agents

Event Publications

1 September 2011 PCT application entered the National Phase

  PCT publication WO2010/083414 Priority application(s): WO2010/083414

27 October 2011 Amendment Made

  The nature of the amendment is: Amend the invention title to read Malate salt of N-(4-{ [ 6, 7-bis (methyloxy)-quinolin-4-yl] oxy}phenyl)-N'-(4-fluorophenyl) cyclopropane-1,1-dicarboxamide, and crystalline forms thereof for the treatment of cancer

3 November 2011 Alteration of Name

  The name of the applicant has been altered to Bristol-Myers Squibb Company; Exelixis, Inc.

19 January 2012 Assignment before Grant

  Exelixis, Inc.; Bristol-Myers Squibb Company The application has been assigned to Exelixis, Inc.

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