Owner Aerie Pharmaceuticals, Inc.

Inventors Delong, Mitchell A.; Sturdivant, Jill Marie

Agent Griffith Hack

Pub. Number AU-A-2009340420

PCT Pub. Number WO2010/096123

Priority 12/260,522 29.10.08 US; 12/260,534 29.10.08 US

Filing date 29 October 2009

Wipo publication date 26 August 2010

C07C 279/14 (2006.01) Derivatives of guanidine, i.e. compounds containing the group the singly-bound nitrogen atoms not being part of nitro or nitroso groups

A61K 31/155 (2006.01) - Amidines (), e.g. guanidine (HNC(NH)NH), isourea (HNC(OH)NH), isothiourea (HNC(SH)NH)

A61K 31/5575 (2006.01)

C07C 291/02 (2006.01) Compounds containing carbon and nitrogen and having functional groups not covered by groups

C07C 405/00 (2006.01) Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins