Substituted 4-(1,2,3,4-tetrahydroisochinolin-2-yl)-4oxo-butyric acid amide as KCNQ2/2 modulators

Details for Australian Patent Application No. 2009335340 (hide)

Owner Grunenthal GmbH

Inventors Kuhnert, Sven; Bahrenberg, Gregor; Merla, Beatrix; Schiene, Klaus; Schroder, Wolfgang

Agent Spruson & Ferguson

Pub. Number AU-A-2009335340

PCT Pub. Number WO2010/075973

Priority 08021880.3 17.12.08 EP

Filing date 16 December 2009

Wipo publication date 8 July 2010

International Classifications

C07D 217/06 (2006.01) Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems

A61K 31/472 (2006.01) - Non-condensed isoquinolines, e.g. papaverine

A61K 31/4725 (2006.01)

A61P 25/00 (2006.01) Drugs for disorders of the nervous system

A61P 29/02 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

C07D 217/14 (2006.01) Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems

C07D 401/04 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 401/06 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 405/06 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 409/04 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

Event Publications

4 August 2011 PCT application entered the National Phase

  PCT publication WO2010/075973 Priority application(s): WO2010/075973

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