C-ring modified tricyclic benzonaphthiridinone protein kinase inhibitors and use thereof

Details for Australian Patent Application No. 2009333653 (hide)

Owner MERCK PATENT GMBH

Inventors Xiao, Yufang; Huck, Bayard R.; Sutton, Amanda E.; Richardson, Thomas E.; Karra, Srinivasa R.

Agent Griffith Hack

Pub. Number AU-A-2009333653

PCT Pub. Number WO2010/077530

Priority 61/201,961 17.12.08 US

Filing date 2 December 2009

Wipo publication date 8 July 2010

International Classifications

C07D 471/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

A61K 31/4375 (2006.01)

A61P 35/00 (2006.01) Antineoplastic agents

C07D 471/14 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 491/147 (2006.01) Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups , , or

C07D 495/14 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms

Event Publications

30 June 2011 PCT application entered the National Phase

  PCT publication WO2010/077530 Priority application(s): WO2010/077530

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