Owner F. Hoffmann-La Roche AG

Inventors Li, Jim; Schoenfeld, Ryan Craig; Steiner, Sandra; Talamas, Francisco Xavier

Agent Spruson & Ferguson

Pub. Number AU-A-2009331660

PCT Pub. Number WO2010/072598

Priority 61/156,442 27.02.09 US; 61/139,982 22.12.08 US

Filing date 14 December 2009

Wipo publication date 1 July 2010

C07D 405/04 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

A61K 31/4965 (2006.01) - Non-condensed pyrazines

A61K 31/497 (2006.01)

A61K 31/50 (2006.01) - Pyridazines

A61K 31/513 (2006.01) - having oxo groups directly attached to the heterocyclic ring, e.g. cytosine

A61K 31/53 (2006.01) - having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine

A61P 31/00 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

C07D 237/14 (2006.01) Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings

C07D 239/36 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 239/52 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 239/54 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 241/18 (2006.01) Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings

C07D 253/07 (2006.01) Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group