Owner Taisho Pharmaceutical Co., Ltd.

Inventors Takayama, Tetsuo; Asanuma, Hajime; Wakasugi, Daisuke; Nishikawa, Rie; Sekiguchi, Yoshinori; Kawamura, Madoka; Ono, Naoya; Yabuuchi, Tetsuya; Oi, Takahiro; Oka, Yusuke; Kuroda, Shoichi; Uneuchi, Fumito; Koami, Takeshi

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-A-2009331144

PCT Pub. Number WO2010/074244

Priority 2008-329064 25.12.08 JP

Filing date 25 December 2009

Wipo publication date 1 July 2010

C07D 217/16 (2006.01) Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems

A61K 31/472 (2006.01) - Non-condensed isoquinolines, e.g. papaverine

A61K 31/4725 (2006.01)

A61K 31/498 (2006.01) - Pyrazines or piperazines ortho- or peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine

A61K 31/501 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61P 11/02 (2006.01) Drugs for disorders of the respiratory system

A61P 11/06 (2006.01) Drugs for disorders of the respiratory system

A61P 17/04 (2006.01) Drugs for dermatological disorders

A61P 37/08 (2006.01) Drugs for immunological or allergic disorders

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07D 217/18 (2006.01) Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems

C07D 217/20 (2006.01) Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 405/12 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 409/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 417/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

C07D 471/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups