Owner Janssen Pharmaceutica NV

Inventors Zhang, Xuqing; Hufnagel, Heather Rae; Hou, Cuifen; Johnson, Dana L.; Sui, Zhihua; Fegely, Barry; Breslin, David

Agent Shelston IP

Pub. Number AU-A-2009324723

PCT Pub. Number WO2010/068663

Priority 61/121,272 10.12.08 US; 61/167,295 07.04.09 US

Filing date 9 December 2009

Wipo publication date 17 June 2010

C07D 401/08 (2006.01) Heterocyclic compounds containing two or more hetero rings

A61K 31/4178 (2006.01)

A61K 31/422 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/4427 (2006.01) - containing further heterocyclic ring systems

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61P 7/12 (2006.01) Drugs for disorders of the blood or the extracellular fluid

C07D 403/08 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 407/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group

C07D 409/08 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 413/08 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 417/08 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

C07D 417/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group