Owner F. Hoffmann-La Roche AG

Inventors Firooznia, Fariborz; Gillespie, Paul; Lin, Tai-An; Mertz, Eric; Sidduri, Achyutharao; So, Sung-Sau; Tan, Jenny; Thakkar, Kshitij Chhabilbhai

Agent Davies Collison Cave

Pub. Number AU-A-2009315713

PCT Pub. Number WO2010/055005

Priority 61/222,235 01.07.09 US; 61/115,147 17.11.08 US

Filing date 9 November 2009

Wipo publication date 20 May 2010

C07C 57/58 (2006.01) Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms

A61K 31/192 (2006.01)

A61K 31/216 (2006.01)

A61K 31/277 (2006.01)

A61K 31/36 (2006.01)

A61P 11/06 (2006.01) Drugs for disorders of the respiratory system

C07C 69/78 (2006.01) Esters of carboxylic acids

C07C 231/12 (2006.01) Preparation of carboxylic acid amides

C07C 255/57 (2006.01) Carboxylic acid nitriles

C07C 311/16 (2006.01) Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups

C07C 317/24 (2006.01) Sulfones

C07D 231/12 (2006.01) Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings

C07D 257/04 (2006.01) Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms

C07D 295/26 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 317/70 (2006.01) Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms