Pyridine, bicyclic pyridine and related analogs as sirtuin modulators

Details for Australian Patent Application No. 2009314310 (hide)

Owner Sirtris Pharmaceuticals, Inc.

Inventors Narayan, Radha; Disch, Jeremy S.; Perni, Robert B.; Vu, Chi B.

Agent Davies Collison Cave

Pub. Number AU-A-2009314310

PCT Pub. Number WO2010/056549

Priority 61/197,595 29.10.08 US

Filing date 29 October 2009

Wipo publication date 20 May 2010

International Classifications

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

A61K 31/14 (2006.01) - Quaternary ammonium compounds, e.g. edrophonium, choline

A61K 31/4427 (2006.01) - containing further heterocyclic ring systems

A61K 31/47 (2006.01) - Quinolines

A61K 31/4709 (2006.01) - Non-condensed quinolines containing further heterocyclic rings

A61K 31/4995 (2006.01) - Pyrazines or piperazines forming part of bridged ring systems

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/5377 (2006.01)

A61P 3/00 (2006.01) Drugs for disorders of the metabolism

A61P 3/10 (2006.01) Drugs for disorders of the metabolism

A61P 5/50 (2006.01) Drugs for disorders of the endocrine system

A61P 7/00 (2006.01) Drugs for disorders of the blood or the extracellular fluid

A61P 9/00 (2006.01) Drugs for disorders of the cardiovascular system

A61P 17/00 (2006.01) Drugs for dermatological disorders

A61P 25/00 (2006.01) Drugs for disorders of the nervous system

A61P 27/00 (2006.01) Drugs for disorders of the senses

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

A61P 35/00 (2006.01) Antineoplastic agents

C07D 213/16 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/81 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 215/16 (2006.01) Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems

C07D 401/14 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

Event Publications

16 June 2011 PCT application entered the National Phase

  PCT publication WO2010/056549 Priority application(s): WO2010/056549

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