Owner Amgen Inc.

Inventors Brown, Sean P.; Dransfield, Paul; Du, Xiaohui; Fu, Zice; Houze, Jonathan; Jiao, Xianyun; Lai, SuJen; Li, An-Rong; Liu, Jiwen; Ma, Zhihua; Medina, Julio C.; Pattaropong, Vatee; Shen, Wang; Vimolratana, Marc; Wang, Yingcai; Wang, Zhongyu; Yu, Ming; Zhu, Liusheng

Agent Shelston IP

Pub. Number AU-B-2009303475

PCT Pub. Number WO2010/045258

Priority 61/196,271 15.10.08 US

Filing date 13 October 2009

Wipo publication date 22 April 2010

Acceptance publication date 13 September 2012

C07C 62/34 Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings and containing any of the groups OH, O-metal, CHO, keto, ether, groups, groups, or groups

A61K 31/185 - Acids

A61K 31/33 - Heterocyclic compounds

A61P 3/10 Drugs for disorders of the metabolism

C07D 221/00 Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups

C07D 231/00 Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings

C07D 249/00 Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms

C07D 271/00 Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms

C07D 277/00 Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D 311/00 Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings