Cyclohexyl amide derivatives and their use as CRF-1 receptor antagonists

Details for Australian Patent Application No. 2009279089 (hide)

Owner Novartis AG

Inventors Beattie, David; Colson, Anny-Odile; Culshaw, Andrew James; Rooney, Lisa; Stanley, Emily; Sviridenko, Lilya

Agent Davies Collison Cave

Pub. Number AU-B-2009279089

PCT Pub. Number WO2010/015655

Priority 09150543.8 14.01.09 EP; 61/205,139 14.01.09 US; 08162006.4 07.08.08 EP

Filing date 5 August 2009

Wipo publication date 11 February 2010

Acceptance publication date 23 August 2012

International Classifications

C07C 233/79 Carboxylic acid amides

A61K 31/166 - having the carbon atom of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol

A61K 31/427 - not condensed and containing further heterocyclic rings

A61K 31/44 - Non-condensed pyridines

A61P 1/00 Drugs for disorders of the alimentary tract or the digestive system

C07C 255/58 Carboxylic acid nitriles

C07C 311/39 Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups

C07D 213/74 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/75 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/84 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 277/42 Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

Event Publications

17 February 2011 PCT application entered the National Phase

  PCT publication WO2010/015655 Priority application(s): WO2010/015655

23 August 2012 Application Accepted

  Published as AU-B-2009279089

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