Novel macrocyclic inhibitors of hepatitis C virus replication

Details for Australian Patent Application No. 2009249443 (hide)

Owner InterMune, Inc.

Inventors Beigelman, Leonid; Buckman, Brad; Porter, Steven B.; Seiwert, Scott; Stoycheva, Antitsa Dimitrova; Serebryany, Vladimir; Bradford, Williamson Ziegler

Agent Davies Collison Cave

Pub. Number AU-A-2009249443

PCT Pub. Number WO2009/142842

Priority 61/150,693 06.02.09 US; 61/105,751 15.10.08 US; 61/143,728 09.01.09 US; 61/045,220 15.04.08 US; 61/105,736 15.10.08 US

Filing date 14 April 2009

Wipo publication date 26 November 2009

International Classifications

C07D 245/04 (2006.01) Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms

A61K 31/407 (2006.01) - condensed with heterocyclic ring systems, e.g. ketorolac, physostigmine

A61K 31/4709 (2006.01) - Non-condensed quinolines containing further heterocyclic rings

A61K 31/4725 (2006.01)

A61K 31/4738 (2006.01) - ortho- or peri-condensed with heterocyclic ring systems

A61K 31/517 (2006.01) - ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine

A61K 31/7056 (2006.01)

A61K 38/05 (2006.01) Medicinal preparations containing peptides - Dipeptides

A61K 38/06 (2006.01) Medicinal preparations containing peptides - Tripeptides

A61K 38/21 (2006.01) Medicinal preparations containing peptides - Interferons

A61P 1/16 (2006.01) Drugs for disorders of the alimentary tract or the digestive system

A61P 31/14 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

C07D 471/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 487/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

C07K 5/12 (2006.01) Peptides having up to four amino acids in a fully defined sequence

C12N 9/99 (2006.01) Enzymes, e.g. ligases (6.) - Enzyme inactivation by chemical treatment

Event Publications

11 November 2010 PCT application entered the National Phase

  PCT publication WO2009/142842 Priority application(s): WO2009/142842

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