Owner INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC.

Inventors Yamaguchi, Youichi; Yanase, Takeshi; Muto, Susumu; Itai, Akiko

Agent Collison & Co

Pub. Number AU-A-2009234899

PCT Pub. Number WO2009/125606

Priority 2008-104152 11.04.08 JP

Filing date 13 April 2009

Wipo publication date 15 October 2009

C07C 59/66 (2006.01) Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O-metal, CHO, keto, ether, groups, groups, or groups

A61K 31/192 (2006.01)

A61K 31/196 (2006.01)

A61K 31/197 (2006.01)

A61K 31/36 (2006.01)

A61K 31/402 (2006.01) - 1-aryl-substituted, e.g. piretanide

A61K 31/41 (2006.01) - having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole

A61K 31/4453 (2006.01) - only substituted in position 1, e.g. propipocaine, diperodon

A61K 31/451 (2006.01) - having a carbocyclic ring directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine

A61K 31/495 (2006.01) - having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine

A61K 31/54 (2006.01) - having six-membered rings with at least one nitrogen and at least one sulfur as the ring hetero atoms, e.g. sulthiame

A61K 31/55 (2006.01) - having seven-membered rings, e.g. azelastine, pentylenetetrazole

C07C 59/68 (2006.01) Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O-metal, CHO, keto, ether, groups, groups, or groups

C07C 59/70 (2006.01) Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O-metal, CHO, keto, ether, groups, groups, or groups

C07C 65/24 (2006.01) Compounds having carboxyl groups bound to carbon atoms of six-membered aromatic rings and containing any of the groups OH, O-metal, CHO, keto, ether, groups, groups, or groups

C07C 205/56 (2006.01) Compounds containing nitro groups bound to a carbon skeleton

C07C 229/42 (2006.01) Compounds containing amino and carboxyl groups bound to the same carbon skeleton

C07C 233/25 (2006.01) Carboxylic acid amides

C07C 233/56 (2006.01) Carboxylic acid amides

C07C 311/08 (2006.01) Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups

C07C 311/29 (2006.01) Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups

C07C 317/22 (2006.01) Sulfones

C07C 323/12 (2006.01) Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups