Tetrazole-substituted arylamide derivatives and their use as P2x3 and/or P2x2/3 purinergic receptor antagonists

Details for Australian Patent Application No. 2008337665 (hide)

Owner F. Hoffmann-La Roche AG

Inventors Dillon, Michael Patrick; Chen, Li; Feng, Lichun; Hawley, Ronald Charles; Yang, Minmin

Agent Davies Collison Cave

Pub. Number AU-A-2008337665

PCT Pub. Number WO2009/077371

Priority 61/007,891 17.12.07 US

Filing date 8 December 2008

Wipo publication date 25 June 2009

International Classifications

C07D 257/08 (2006.01) Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms

A61K 31/41 (2006.01) - having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole

A61K 31/497 (2006.01)

A61P 11/00 (2006.01) Drugs for disorders of the respiratory system

A61P 13/02 (2006.01) Drugs for disorders of the urinary system

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

C07D 403/10 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 403/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 403/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

Event Publications

24 June 2010 PCT application entered the National Phase

  PCT publication WO2009/077371 Priority application(s): WO2009/077371

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