Owner Amgen Inc.

Inventors Hong, Fang-Tsao; Zeng, Qingping; Monenschein, Holger; Falsey, James R.; Wang, Xianghong; Dominguez, Celia; Yao, Guomin; Zhang, Dawei; Reichelt, Andreas; Bourbeau, Matthew P.; Wohlhieter, George E.; Rider, James; Allen, John G.

Agent Shelston IP

Pub. Number AU-B-2008276521

PCT Pub. Number WO2009/011880

Priority 60/959,972 17.07.07 US

Filing date 16 July 2008

Wipo publication date 22 January 2009

Acceptance publication date 3 November 2011

C07D 263/48 (2006.01) Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings

A61K 31/41 (2006.01) - having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole

A61K 31/5377 (2006.01)

A61P 35/00 (2006.01) Antineoplastic agents

C07D 401/04 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/04 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 413/04 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 413/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 417/04 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group