Preparation of N-alkylated opiates by reductive amination

Details for Australian Patent Application No. 2008276385 (hide)

Owner Mallinckrodt Inc.

Inventors Cantrell, Gary L.; Orr, Brian; Jiang, Tao; Grote, Christopher W.

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-A-2008276385

PCT Pub. Number WO2009/012005

Priority 60/950,127 17.07.07 US

Filing date 16 June 2008

Wipo publication date 22 January 2009

International Classifications

C07D 489/02 (2006.01) Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:

C07D 489/08 (2006.01) Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:

Event Publications

11 February 2010 PCT application entered the National Phase

  PCT publication WO2009/012005 Priority application(s): WO2009/012005

3 November 2011 Assignment before Grant

  Mallinckrodt Inc. The application has been assigned to Mallinckrodt LLC Assignments before Grant, Section 113

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