Owner Kyowa Hakko Kirin Co., Ltd.

Inventors Shimada, Takashi; Yoshida, Hitoshi; Urakawa, Itaru; Hasegawa, Hisashi; Yamazaki, Yuji; Aono, Yukiko; Yamashita, Takeyoshi

Agent FB Rice

Pub. Number AU-A-2008215346

PCT Pub. Number WO2008/099969

Priority 2007-034018 14.02.07 JP

Filing date 14 February 2008

Wipo publication date 21 August 2008

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

A61K 39/395 (2006.01) Medicinal preparations containing antigens or antibodies - Antibodies

A61P 3/00 (2006.01) Drugs for disorders of the metabolism

A61P 3/02 (2006.01) Drugs for disorders of the metabolism

A61P 5/18 (2006.01) Drugs for disorders of the endocrine system

A61P 19/08 (2006.01) Drugs for skeletal disorders

A61P 19/10 (2006.01) Drugs for skeletal disorders

C07K 16/22 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies

C12N 1/15 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/19 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/21 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 5/10 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

C12P 21/08 (2006.01) Preparation of peptides or proteins - Monoclonal antibodies