Owner Vertex Pharmaceuticals Incorporated

Inventors Wang, Tiansheng; Duffy, John; Bennani, Yousseff; Salituro, Francesco

Agent Baldwins

Pub. Number AU-A-2007338574

PCT Pub. Number WO2008/079521

Priority 60/855,862 01.11.06 US

Filing date 31 October 2007

Wipo publication date 3 July 2008

C07D 471/16 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

A61K 31/395 (2006.01) - having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins

A61K 31/435 (2006.01) - having six-membered rings with one nitrogen as the only ring hetero atom

A61K 31/495 (2006.01) - having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine

A61P 11/06 (2006.01) Drugs for disorders of the respiratory system

A61P 37/06 (2006.01) Drugs for immunological or allergic disorders

C07D 471/22 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 487/16 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups