Owner Eisai R & D Management Co., Ltd.

Inventors Nagai, Mitsuo; Nara, Kazumasa; Abe, Shinya; Wakasugi, Kazunori; Sakaguchi, Takahisa; Matsushima, Tomohiro; Shirotori, Shuji; Kamada, Atsushi

Agent Davies Collison Cave

Pub. Number AU-B-2007289787

PCT Pub. Number WO2008/026577

Priority 60/855117 30.10.06 US; 60/824192 31.08.06 US; 2006-285327 19.10.06 JP

Filing date 28 August 2007

Wipo publication date 6 March 2008

Acceptance publication date 29 March 2012

C07D 213/73 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

A61K 31/4427 (2006.01) - containing further heterocyclic ring systems

A61K 31/4439 (2006.01)

A61K 31/4545 (2006.01)

A61K 31/496 (2006.01) - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene

A61P 9/00 (2006.01) Drugs for disorders of the cardiovascular system

A61P 35/00 (2006.01) Antineoplastic agents

A61P 35/04 (2006.01) Antineoplastic agents

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07D 213/75 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/81 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings