Owner Juridical Foundation The ChemoSero-Therapeutic Research Institute Astellas Pharma Inc.

Inventors Higuchi, Hirofumi; Torikai, Masaharu; Yamamoto, Nobuchika; Sakai, Fumihiko; Nakashima, Toshihiro

Agent Davies Collison Cave

Pub. Number AU-A-2007268591

PCT Pub. Number WO2007/139164

Priority 2006-152892 31.05.06 JP

Filing date 30 May 2007

Wipo publication date 6 December 2007

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

A61K 39/395 (2006.01) Medicinal preparations containing antigens or antibodies - Antibodies

A61P 19/02 (2006.01) Drugs for skeletal disorders

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

A61P 37/06 (2006.01) Drugs for immunological or allergic disorders

C07K 16/18 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies - against material from animals or humans

C07K 16/46 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies - Hybrid immunoglobulins

C12N 1/15 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/19 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/21 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 5/10 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

C12P 21/08 (2006.01) Preparation of peptides or proteins - Monoclonal antibodies

G01N 33/53 (2006.01) Investigating or analysing materials by specific methods not covered by groups - Immunoassay