Spirocyclic nitriles as protease inhibitors

Details for Australian Patent Application No. 2007267470 (hide)

Owner Sanofi-Aventis

Inventors Kohlmann, Anna; Wagner, Michael; Schudok, Manfred; Bauer, Armin

Agent Watermark

Pub. Number AU-B-2007267470

PCT Pub. Number WO2007/137738

Priority 10 2006 025 630.1 01.06.06 DE

Filing date 23 May 2007

Wipo publication date 6 December 2007

Acceptance publication date 20 September 2012

International Classifications

C07D 211/66 Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

A61K 31/438 - the ring being spiro-condensed with carbocyclic or heterocyclic ring systems

A61P 19/00 Drugs for skeletal disorders

A61P 35/00 Antineoplastic agents

C07C 237/24 Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups

C07D 213/26 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 231/54 Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings

C07D 263/52 Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings

C07D 295/215 Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 295/26 Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 317/72 Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms

C07D 471/10 Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 491/10 Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups , , or

C07D 498/10 Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms

Event Publications

8 January 2009 PCT application entered the National Phase

  PCT publication WO2007/137738 Priority application(s): WO2007/137738

20 September 2012 Application Accepted

  Published as AU-B-2007267470

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